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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC24C All Species: 20.91
Human Site: T955 Identified Species: 32.86
UniProt: P53992 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53992 NP_004913.2 1094 118325 T955 Y P R L L P L T K S P V E S T
Chimpanzee Pan troglodytes XP_001145058 1094 118246 T955 Y P R L L P L T K S P V E S T
Rhesus Macaque Macaca mulatta XP_001104565 998 107625 Q867 D D R A Y V R Q L V T S M D V
Dog Lupus familis XP_850963 1096 118584 T957 Y P R L L P L T K S P I E S A
Cat Felis silvestris
Mouse Mus musculus Q3U2P1 1090 118764 L955 N L S D E G A L N I N D R T I
Rat Rattus norvegicus NP_001102926 1095 118506 T956 Y P R L L P L T K S P L D S T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513100 1030 112379 T899 T M D P T S L T F P T A V R C
Chicken Gallus gallus XP_421617 1147 124543 T1008 Y P R L L P L T K A D V D S D
Frog Xenopus laevis NP_001087832 1126 123503 S987 Y P R L L P L S K M D P S N D
Zebra Danio Brachydanio rerio XP_700597 1315 142554 L1178 Y P R L L P L L D A E S T S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392952 1276 140829 H1136 Y P R L L P L H D V D L Q D T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783728 1150 123558 H1011 Y P R L L P V H D I D V N S E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M081 1080 116273 D943 M I S V H D L D V K D T E G S
Baker's Yeast Sacchar. cerevisiae P53953 876 98925 E745 N A T I S L F E R Y G L Y L I
Red Bread Mold Neurospora crassa Q7S4P3 950 103512 P819 S Q I V L P P P M N L S S E R
Conservation
Percent
Protein Identity: 100 99.5 86.9 94.8 N.A. 26.9 92 N.A. 51.9 75.4 69 59.5 N.A. N.A. 44.5 N.A. 52.6
Protein Similarity: 100 99.7 87.9 96.1 N.A. 45.8 94.4 N.A. 66.2 82.3 78.1 69 N.A. N.A. 59.4 N.A. 64.3
P-Site Identity: 100 100 6.6 86.6 N.A. 0 86.6 N.A. 13.3 73.3 53.3 53.3 N.A. N.A. 53.3 N.A. 53.3
P-Site Similarity: 100 100 6.6 93.3 N.A. 6.6 100 N.A. 13.3 86.6 66.6 60 N.A. N.A. 66.6 N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. 33 22.4 30
Protein Similarity: N.A. N.A. N.A. 49.3 41.1 47
P-Site Identity: N.A. N.A. N.A. 13.3 0 13.3
P-Site Similarity: N.A. N.A. N.A. 26.6 20 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 7 0 0 7 0 0 14 0 7 0 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % C
% Asp: 7 7 7 7 0 7 0 7 20 0 34 7 14 14 14 % D
% Glu: 0 0 0 0 7 0 0 7 0 0 7 0 27 7 7 % E
% Phe: 0 0 0 0 0 0 7 0 7 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 7 0 0 0 0 7 0 0 7 0 % G
% His: 0 0 0 0 7 0 0 14 0 0 0 0 0 0 0 % H
% Ile: 0 7 7 7 0 0 0 0 0 14 0 7 0 0 14 % I
% Lys: 0 0 0 0 0 0 0 0 40 7 0 0 0 0 0 % K
% Leu: 0 7 0 60 67 7 67 14 7 0 7 20 0 7 7 % L
% Met: 7 7 0 0 0 0 0 0 7 7 0 0 7 0 0 % M
% Asn: 14 0 0 0 0 0 0 0 7 7 7 0 7 7 0 % N
% Pro: 0 60 0 7 0 67 7 7 0 7 27 7 0 0 0 % P
% Gln: 0 7 0 0 0 0 0 7 0 0 0 0 7 0 0 % Q
% Arg: 0 0 67 0 0 0 7 0 7 0 0 0 7 7 7 % R
% Ser: 7 0 14 0 7 7 0 7 0 27 0 20 14 47 7 % S
% Thr: 7 0 7 0 7 0 0 40 0 0 14 7 7 7 27 % T
% Val: 0 0 0 14 0 7 7 0 7 14 0 27 7 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 60 0 0 0 7 0 0 0 0 7 0 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _